Endoglin 抗体 (APC)
Quick Overview for Endoglin 抗体 (APC) (ABIN303549)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Size-exclusion chromatography
-
免疫原
- Recombinant Vaccinia virus containing the human CD105 cDNA
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. -
有效期
- 12 months
-
-
- Endoglin (ENG)
-
别名
- CD105 / Endoglin
-
背景
- CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1
-
UniProt
- P17813
抗原
-